TPST2P1

Across TCGA pan-cancer cohorts, TPST2P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TPST2P1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TPST2P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TPST2P1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

LUSC, KIRP, and LIHC are the cancer types where TPST2P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TPST2P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.037	<.001	4	view →
KIRP	All	All	−0.015	.006	3	view →
LIHC	All	All	+0.006	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

TPST2P1–LUSC

Open the LUSC breakdown →