TPST1

Across TCGA cell cohorts, TPST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,098 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TPST1-associated GO terms across cancer lineages are Protein sulfation, Collagen fibril organization, and Regulation of glycolytic process through fructose-6-phosphate. Each is linked with TPST1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TPST1-to-partner and partner-to-TPST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sulfation grouped by TPST1-low versus TPST1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPST1→partner) and Y-score (partner→TPST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein sulfation →	+1.141	+1.329	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Collagen fibril organization →	+0.355	+2.075	<.001	.007	3	14
OESOPHAGUS	Regulation of glycolytic process through fructose-6-phosphate →	+0.152	+1.407	.001	.002	3	13
OESOPHAGUS	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.152	+1.407	.001	.002	3	13
BONE	Response to hydrostatic pressure →	+0.172	+1.270	<.001	<.001	3	13
CNS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.071	+1.470	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,098 associations by consensus.

Protein sulfation by TPST1 expression — BREAST

Explore this box plot interactively →