TPSP2

Across TCGA pan-cancer cohorts, TPSP2 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TPSP2 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher TPSP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TPSP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

LUSC, KIRC, and THCA are the cancer types where TPSP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Quartile	III,IV	0.361	0.703	.005	40	view →
KIRC	DFS	Median	All	0.554	0.690	.003	35	view →
THCA	DFS	Quartile	III,IV	0.588	0.885	.009	33	view →
HNSC	OS	Median	II,III,IV	0.558	0.275	.002	32	view →
PAAD	OS	Median	All	0.462	0.697	.002	32	view →
ACC	DFS	Median	III,IV	0.275	0.734	<.001	32	view →
CESC	OS	Tertile	II,III,IV	0.634	0.271	.009	28	view →
BLCA	DFS	Median	All	0.551	0.465	.024	20	view →
ESCA	DFS	Median	II,III,IV	0.293	1.000	.002	18	view →
OV	DFS	Quartile	II,III,IV	0.475	0.569	.025	18	view →
PRAD	DFS	Median	All	0.698	0.883	<.001	18	view →
PCPG	OS	Tertile	All	0.916	0.991	.011	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TPSP2–LUSC (DFS)

Open the LUSC breakdown →