TPSG1

Across TCGA pan-cancer cohorts, TPSG1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TPSG1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TPSG1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TPSG1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, LUAD, and GBM are the cancer types where TPSG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	1.000	0.479	.014	28	view →
LUAD	DFS	Tertile	II,III,IV	0.727	0.160	.024	6	view →
GBM	OS	Median	All	0.564	0.275	.022	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TPSG1–UCEC (OS)

Open the UCEC breakdown →