TPSG1

Across TCGA patient cohorts, TPSG1 mutation is significantly associated with the RNA expression of many other genes, with 79 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TPSG1-associated genes across cancer lineages are LINC01746, RN7SL98P, and MIR6802. Each is linked with TPSG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPSG1-to-partner and partner-to-TPSG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01746 grouped by TPSG1-low versus TPSG1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPSG1→partner) and Y-score (partner→TPSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01746 →	+0.059	+3.771	<.001	.002	3	2
UCEC	RN7SL98P →	+0.146	+3.523	.002	.001	3	2
SKCM	MIR6802 →	+0.179	+4.411	<.001	.005	3	2
LUSC	MIR4704 →	+0.305	+7.924	<.001	.008	3	2
UCEC	BNIP3P4 →	+0.081	+3.484	<.001	.004	3	1
UCEC	RNU4-5P →	+0.414	+3.113	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

LINC01746 by TPSG1 expression — SKCM

Explore this box plot interactively →