TPSG1

Across TCGA cell cohorts, TPSG1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TPSG1-associated genes across cancer lineages are CEACAM4, DBX1, and LHCGR. Each is linked with TPSG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPSG1-to-partner and partner-to-TPSG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEACAM4 grouped by TPSG1-low versus TPSG1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPSG1→partner) and Y-score (partner→TPSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CEACAM4 →	+0.056	+4.927	<.001	.001	3	1
BLOOD_Lymphoma	DBX1 →	+0.247	+5.169	<.001	.001	3	1
BLOOD_Lymphoma	LHCGR →	+0.030	+4.350	.007	.005	3	1
BLOOD_Lymphoma	MMP26 →	+0.041	+4.643	.009	.005	3	1
BLOOD_Lymphoma	RNASE3 →	+0.047	+4.523	.003	.004	3	1
BLOOD_Lymphoma	ACOT6 →	+0.066	+4.523	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CEACAM4 by TPSG1 expression — BLOOD_Lymphoma

Explore this box plot interactively →