Across TCGA patient cohorts, TPSB2 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPSB2-associated genes across cancer lineages are RNU6-694P, SOD1P2, and REXO1L8P. Each is linked with TPSB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPSB2-to-partner and partner-to-TPSB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPSB2→partner) and Y-score (partner→TPSB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-694P →	+0.356	+4.308	<.001	.009	3	1
COAD	SOD1P2 →	+0.244	+4.730	<.001	.001	3	1
COAD	REXO1L8P →	+0.031	+5.557	<.001	.001	3	1
SKCM	KRTAP12-6P →	+0.149	+5.993	<.001	.001	3	1
SKCM	VDAC2P4 →	+0.072	+4.661	.004	.004	3	1
SKCM	NMBR-AS1 →	+0.159	+4.513	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

Exploration

TPSB2 survival (RNA) · tumor vs normal (RNA) · all TPSB2 data types