TPSAB1

Across TCGA patient cohorts, TPSAB1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,873 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TPSAB1-associated genes across cancer lineages are TPSB2, H2BC17, and AURKA. Each is linked with TPSAB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TPSAB1-to-partner and partner-to-TPSAB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPSAB1 versus TPSB2 in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPSAB1→partner) and Y-score (partner→TPSAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TPSB2 →	+2.125	+0.978	<.001	<.001	3	5
HNSC	H2BC17 →	-1.068	-0.464	.005	.005	3	5
LUAD	AURKA →	-1.128	-0.608	<.001	<.001	3	5
BRCA	TPSD1 →	+1.390	+0.675	<.001	<.001	3	5
BRCA	CTSG →	+1.544	+0.780	<.001	<.001	3	4
CCRCC	BMX →	+0.903	+0.461	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,873 associations by consensus.

TPSAB1 vs TPSB2 — BRCA

Explore this scatter interactively →