TPSAB1

Across TCGA cell cohorts, TPSAB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,580 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TPSAB1-associated GO terms across cancer lineages are Aldosterone biosynthetic process, Tertiary alcohol biosynthetic process, and Aldosterone metabolic process. Each is linked with TPSAB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TPSAB1-to-partner and partner-to-TPSAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aldosterone biosynthetic process grouped by TPSAB1-low versus TPSAB1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPSAB1→partner) and Y-score (partner→TPSAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Aldosterone biosynthetic process →	+1.681	+1.199	<.001	<.001	3	7
LIVER	Tertiary alcohol biosynthetic process →	+1.867	+0.130	<.001	.007	3	6
BONE	Aldosterone metabolic process →	+1.527	+1.125	<.001	.001	3	6
LIVER	Cortisol biosynthetic process →	+1.867	+0.130	<.001	.007	3	6
BONE	Mineralocorticoid biosynthetic process →	+1.766	+1.199	<.001	<.001	3	6
BONE	Glucocorticoid biosynthetic process →	+1.380	+1.214	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,580 associations by consensus.

Aldosterone biosynthetic process by TPSAB1 expression — BONE

Explore this box plot interactively →