Across TCGA pan-cancer cohorts, TPRX2P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TPRX2P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TPRX2P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TPRX2P is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.
HNSC and LIHC are the cancer types where TPRX2P tumor–normal differential expression is most reproducible.