TPRKBP2

Across TCGA patient cohorts, TPRKBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,735 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TPRKBP2-associated GO terms across cancer lineages are DNA biosynthetic process, Nuclear-transcribed mRNA catabolic process, and Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Each is linked with TPRKBP2 in more than 28 cancer types. Because this analysis shows association rather than direction, both TPRKBP2-to-partner and partner-to-TPRKBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA biosynthetic process grouped by TPRKBP2-low versus TPRKBP2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPRKBP2→partner) and Y-score (partner→TPRKBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	DNA biosynthetic process →	+0.055	+0.206	.003	.004	3	29
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.062	+0.208	.003	.002	3	29
STAD	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.052	+0.215	<.001	<.001	3	29
ESCA	Regulation of telomere maintenance →	+0.086	+0.340	<.001	<.001	3	29
STAD	Maintenance of cell number →	+0.043	+0.233	<.001	<.001	3	28
DLBC	Rescue of stalled ribosome →	+0.070	+0.223	.001	.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,735 associations by consensus.

DNA biosynthetic process by TPRKBP2 expression — DLBC

Explore this box plot interactively →