TPRG1L

Across TCGA pan-cancer cohorts, TPRG1L Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TPRG1L data layer compared with 21 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TPRG1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TPRG1L expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD, PRAD, and UCEC are the cancer types where TPRG1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.168	0.806	.002	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	DFS	Median	All	1.000	0.633	.025	6	view →
SKCM	DFS	Median	III,IV	0.046	0.648	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TPRG1L–COAD (OS)

Open the COAD breakdown →