TPRG1L

Across TCGA cell cohorts, TPRG1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,480 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TPRG1L-associated GO terms across cancer lineages are Positive regulation of autophagy, Regulation of vacuole organization, and Regulation of neuron apoptotic process. Each is linked with TPRG1L in more than 13 cancer types. Because this analysis shows association rather than direction, both TPRG1L-to-partner and partner-to-TPRG1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by TPRG1L-low versus TPRG1L-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPRG1L→partner) and Y-score (partner→TPRG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of autophagy →	+0.044	+0.868	.001	<.001	3	14
BLOOD_Myeloma	Regulation of vacuole organization →	+0.065	+0.907	<.001	.002	3	12
BONE	Regulation of neuron apoptotic process →	+0.108	+1.088	.001	<.001	3	11
LUNG_SCLC	Regulation of autophagosome assembly →	+0.049	+0.902	.002	<.001	2	12
SOFT_TISSUE	Cytosol to Golgi apparatus transport →	+0.076	+0.525	<.001	.002	3	11
SKIN	Response to insulin →	+0.036	+0.643	.001	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,480 associations by consensus.

Positive regulation of autophagy by TPRG1L expression — OVARY

Explore this box plot interactively →