Across TCGA cell cohorts, TPRG1 mutation is significantly associated with the mutation status of many other genes, with 821 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TPRG1-associated genes across cancer lineages are CDT1, ZBTB20, and ZNF710. Each is linked with TPRG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TPRG1-to-partner and partner-to-TPRG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPRG1→partner) and Y-score (partner→TPRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CDT1 →	+4.459	+5.277	.005	.005	1	3
CNS	ZBTB20 →	+5.044	+5.614	.003	.003	1	3
BLOOD_Lymphoma	ZNF710 →	+5.014	+5.584	.003	.003	1	3
BLOOD_Lymphoma	NOP58 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	BAX →	+6.014	+6.014	.001	.001	1	3
CNS	RWDD4 →	+6.044	+6.044	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 821 associations by consensus.

Exploration

TPRG1 survival (RNA) · tumor vs normal (RNA) · all TPRG1 data types