TPPP3

Across TCGA patient cohorts, TPPP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,755 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TPPP3-associated proteins across cancer lineages are TPPP, TPPP3_S162, and PGM5. Each is linked with TPPP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both TPPP3-to-partner and partner-to-TPPP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPPP3 versus TPPP in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP3→partner) and Y-score (partner→TPPP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TPPP →	+0.825	+1.384	.001	<.001	3	8
CCRCC	TPPP3_S162 →	+1.561	+1.522	<.001	<.001	3	8
CCRCC	PGM5 →	+0.754	+1.026	<.001	<.001	3	7
BRCA	TPPP_T14 →	+1.122	+1.349	<.001	<.001	3	6
UCEC	RPGR_S961 →	+0.635	+2.392	<.001	<.001	3	6
UCEC	AGR3 →	+1.134	+2.677	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,755 associations by consensus.

TPPP3 vs TPPP — GBM

Explore this scatter interactively →