TPPP3

Across TCGA patient cohorts, TPPP3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,747 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TPPP3-associated genes across cancer lineages are PIFO, MYOM1, and CASQ2. Each is linked with TPPP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both TPPP3-to-partner and partner-to-TPPP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPPP3 versus PIFO in UCEC, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP3→partner) and Y-score (partner→TPPP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIFO →	+2.132	+1.801	<.001	<.001	3	8
CCRCC	MYOM1 →	+0.819	+0.682	<.001	<.001	3	7
COAD	CASQ2 →	+1.262	+0.471	<.001	<.001	3	7
UCEC	LRRC36 →	+0.895	+1.305	<.001	<.001	3	7
UCEC	RSPH4A →	+2.145	+1.818	<.001	<.001	3	7
UCEC	ZDHHC1 →	+0.856	+1.232	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,747 associations by consensus.

TPPP3 vs PIFO — UCEC

Explore this scatter interactively →