TPPP3

Across TCGA cell cohorts, TPPP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,662 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TPPP3-associated GO terms across cancer lineages are COPII-coated vesicle budding, Intrinsic apoptotic signaling pathway, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with TPPP3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TPPP3-to-partner and partner-to-TPPP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle budding grouped by TPPP3-low versus TPPP3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP3→partner) and Y-score (partner→TPPP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	COPII-coated vesicle budding →	+0.069	+1.070	<.001	.001	3	9
LUNG_NSCLC_LUAD	Intrinsic apoptotic signaling pathway →	+0.044	+1.346	.004	.004	3	9
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.075	+0.972	.001	.003	3	8
OVARY	Negative regulation of myoblast fusion →	+0.105	+1.331	<.001	<.001	3	8
PANCREAS	Pallium development →	+0.059	+1.773	.004	<.001	3	8
CNS	Electron transport chain →	+0.073	+1.517	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,662 associations by consensus.

COPII-coated vesicle budding by TPPP3 expression — SKIN

Explore this box plot interactively →