Q-omics provides the consensus-scored TPMTP4 profile across patient tissues and cancer cell-line models. TPMTP4 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in READ. Additionally, TPMTP4 RNA expression shows 6,235 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight READ, and STAD as cancer lineages where TPMTP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes TPMTP4 survival associations across molecular data types. TPMTP4 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TPMTP4 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	READ (90)	view →

This table ranks reproducible TPMTP4 RNA expression–survival associations across cancer types. High TPMTP4 expression shows unfavorable associations in READ, KIRC, PAAD, KIRP, OV and GBM. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for TPMTP4 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	II,III,IV	0.173	0.818	<.001	90	view →
KIRC	OS	Tertile	All	0.439	0.652	<.001	87	view →
PAAD	OS	Tertile	All	0.112	0.613	<.001	72	view →
KIRP	DFS	Tertile	II,III,IV	0.122	0.626	.032	18	view →
OV	OS	Tertile	III,IV	0.448	0.685	.044	12	view →
GBM	OS	Tertile	All	0.101	0.413	.035	9	view →

Pink = unfavorable, green = favorable. all 8 lineages →

TPMTP4-READ (OS)

Kaplan–Meier survival curve for TPMTP4 RNA expression in READ: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with TPMTP4 in patient tissues and cancer cell lines. In patient samples, TPMTP4 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	6,235	STAD (6059)	view →
RNA	3,388	COAD (1340)	view →