TPMTP3

Across TCGA pan-cancer cohorts, TPMTP3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated TPMTP3 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TPMTP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TPMTP3 expression acts as an unfavorable survival marker.

ACC, BLCA, and STAD are the cancer types where TPMTP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.144	0.812	<.001	189	view →
BLCA	DFS	Tertile	IV	0.107	0.475	<.001	81	view →
STAD	DFS	Tertile	All	0.518	0.694	<.001	81	view →
KIRC	OS	Tertile	II,III,IV	0.475	0.812	.003	78	view →
UCEC	DFS	Tertile	All	0.402	0.658	<.001	78	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	54	view →
LAML	DFS	Tertile	All	0.161	0.397	.010	36	view →
SKCM	DFS	Tertile	All	0.334	0.772	<.001	33	view →
MESO	OS	Tertile	II,III,IV	0.217	0.575	.014	27	view →
READ	OS	Tertile	III,IV	0.644	0.932	<.001	21	view →
DLBC	OS	Tertile	All	0.613	0.945	.049	9	view →
KIRP	OS	Tertile	All	0.726	0.950	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

TPMTP3–ACC (OS)

Open the ACC breakdown →