TPM4

Across TCGA patient cohorts, TPM4 protein abundance is significantly associated with the RNA expression of many other genes, with 14,228 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TPM4-associated genes across cancer lineages are MYL9, CCN4, and CLEC11A. Each is linked with TPM4 in more than 9 cancer types. Because this analysis shows association rather than direction, both TPM4-to-partner and partner-to-TPM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPM4 versus MYL9 in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPM4→partner) and Y-score (partner→TPM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYL9 →	+1.303	+0.616	<.001	<.001	3	10
BRCA	CCN4 →	+1.423	+0.624	<.001	<.001	3	9
BRCA	CLEC11A →	+1.173	+0.442	<.001	<.001	3	9
BRCA	ASPN →	+2.289	+0.623	<.001	<.001	3	9
BRCA	ACTA2 →	+1.313	+0.599	<.001	<.001	3	9
BRCA	CALD1 →	+1.232	+0.705	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,228 associations by consensus.

TPM4 vs MYL9 — BRCA

Explore this scatter interactively →