TPM4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TPM4 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TPM4-associated genes across cancer lineages are Preadipocytes and NK cells. Each is linked with TPM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPM4-to-partner and partner-to-TPM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by TPM4-low versus TPM4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPM4→partner) and Y-score (partner→TPM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPreadipocytes →+0.045+4.169.015.02731
STADNK cells →+0.009+5.597<.001.04031
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Preadipocytes by TPM4 expression — COAD

Box plot of Preadipocytes in TPM4-low vs TPM4-high samples in COAD.

Explore this box plot interactively →

Exploration