TPM3P9

Across TCGA pan-cancer cohorts, TPM3P9 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TPM3P9’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where TPM3P9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TPM3P9 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BLCA, THCA, and STAD are the cancer types where TPM3P9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TPM3P9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	+1.189	<.001	12	view →
THCA	All	II,III,IV	−0.680	<.001	10	view →
STAD	Female	All	+1.291	<.001	9	view →
COAD	Female	All	+0.769	<.001	9	view →
KIRC	Male	All	+0.361	<.001	8	view →
LIHC	Female	II,III,IV	+1.231	<.001	7	view →
HNSC	Male	All	+0.651	<.001	7	view →
UCEC	All	III,IV	+0.851	.001	6	view →
BRCA	All	II,III,IV	+0.309	<.001	6	view →
CHOL	All	All	+1.853	<.001	5	view →
LUSC	Male	All	+0.640	<.001	5	view →
READ	All	All	+0.696	.002	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TPM3P9–BLCA

Open the BLCA breakdown →