TPM3P6

Across TCGA pan-cancer cohorts, TPM3P6 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TPM3P6 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TPM3P6 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TPM3P6 expression acts as an unfavorable survival marker, although some lineages such as PRAD and DLBC show a favorable association.

ACC, CESC, and LUSC are the cancer types where TPM3P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.277	0.651	<.001	87	view →
CESC	DFS	Median	III,IV	0.401	0.818	<.001	56	view →
LUSC	OS	Median	II,III,IV	0.290	0.678	.001	52	view →
COAD	DFS	Tertile	All	0.615	0.753	.012	31	view →
LIHC	OS	Tertile	All	0.593	0.769	.001	27	view →
PRAD	DFS	Quartile	All	0.940	0.830	.005	22	view →
MESO	DFS	Quartile	II,III,IV	0.154	0.882	.006	15	view →
THCA	DFS	Quartile	IV	0.481	0.915	.007	15	view →
DLBC	OS	Quartile	II,III,IV	0.956	0.270	.017	14	view →
LGG	DFS	Quartile	All	0.232	0.559	<.001	12	view →
ESCA	OS	Tertile	II,III,IV	0.423	1.000	.034	11	view →
SKCM	DFS	Median	All	0.693	0.817	.017	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TPM3P6–ACC (DFS)

Open the ACC breakdown →