Across TCGA patient cohorts, TPM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,621 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TPM2-associated proteins across cancer lineages are SMTN, TAGLN, and VCL. Each is linked with TPM2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TPM2-to-partner and partner-to-TPM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPM2→partner) and Y-score (partner→TPM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SMTN →	+0.832	+1.437	<.001	<.001	3	10
OV	TAGLN →	+1.188	+1.507	<.001	<.001	3	10
UCEC	VCL →	+0.625	+1.575	<.001	<.001	3	10
UCEC	CALD1 →	+1.071	+1.570	<.001	<.001	3	10
BRCA	CALD1_S759 →	+1.366	+1.170	<.001	<.001	3	10
BRCA	CLEC3B →	+0.762	+0.990	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,621 associations by consensus.

Exploration

TPM2 survival (RNA) · tumor vs normal (RNA) · all TPM2 data types