Across TCGA patient cohorts, TPM2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,698 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TPM2-associated genes across cancer lineages are MYL9, DCN, and TGFB3. Each is linked with TPM2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TPM2-to-partner and partner-to-TPM2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPM2→partner) and Y-score (partner→TPM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.456	+1.116	<.001	<.001	3	10
CCRCC	DCN →	+1.887	+1.008	<.001	<.001	3	10
OV	TGFB3 →	+1.383	+0.920	<.001	<.001	3	10
OV	CALD1 →	+1.154	+0.876	<.001	<.001	3	10
OV	AOC3 →	+1.518	+1.023	<.001	<.001	3	10
UCEC	TAGLN →	+2.217	+1.359	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,698 associations by consensus.

Exploration

TPM2 survival (RNA) · tumor vs normal (RNA) · all TPM2 data types