Across TCGA cell cohorts, TPM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,395 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TPM2-associated GO terms across cancer lineages are Regulation of ATP-dependent activity, Positive regulation of cell-substrate adhesion, and Positive regulation of focal adhesion assembly. Each is linked with TPM2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TPM2-to-partner and partner-to-TPM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPM2→partner) and Y-score (partner→TPM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of ATP-dependent activity →	+0.119	+4.167	<.001	<.001	3	12
BONE	Positive regulation of cell-substrate adhesion →	+0.123	+3.355	<.001	<.001	3	9
BONE	Positive regulation of focal adhesion assembly →	+0.289	+4.380	<.001	<.001	3	9
BREAST	Foam cell differentiation →	+0.232	+2.732	.002	<.001	3	9
BONE	Peptidyl-lysine oxidation →	+1.694	+3.963	<.001	<.001	3	8
LUNG_SCLC	Negative regulation of endodermal cell differentiation →	+0.923	+3.046	.009	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,395 associations by consensus.

Exploration

TPM2 survival (RNA) · tumor vs normal (RNA) · all TPM2 data types