Across TCGA patient cohorts, TPK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,114 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TPK1-associated proteins across cancer lineages are RIN3, STK10, and DEF6. Each is linked with TPK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TPK1-to-partner and partner-to-TPK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPK1→partner) and Y-score (partner→TPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RIN3 →	+0.320	+0.343	.002	.001	3	6
UCEC	STK10 →	+0.456	+0.997	<.001	<.001	3	6
GBM	DEF6 →	+0.564	+0.485	<.001	<.001	3	6
LSCC	GIMAP4 →	+0.495	+0.379	<.001	<.001	3	6
UCEC	GIMAP7 →	+0.579	+0.929	<.001	<.001	3	6
GBM	GMIP →	+0.399	+0.462	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,114 associations by consensus.

Exploration

TPK1 survival (RNA) · tumor vs normal (RNA) · all TPK1 data types