Across TCGA cell cohorts, TPK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,853 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TPK1-associated GO terms across cancer lineages are Thiamine metabolic process, Viral genome replication, and Positive regulation of focal adhesion assembly. Each is linked with TPK1 in more than 9 cancer types. Because this analysis shows association rather than direction, both TPK1-to-partner and partner-to-TPK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPK1→partner) and Y-score (partner→TPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Thiamine metabolic process →	+1.336	+1.981	<.001	<.001	3	10
KIDNEY	Viral genome replication →	-0.101	-1.079	.004	.009	3	7
LUNG_NSCLC_LUAD	Positive regulation of focal adhesion assembly →	+0.095	+0.693	.001	.005	2	7
BONE	Negative regulation of double-strand break repair →	-0.090	-0.684	<.001	.003	3	6
STOMACH	Regulation of protection from non-homologous end joining at telomere →	-0.150	-1.173	<.001	<.001	3	6
STOMACH	Negative regulation of protection from non-homologous end joining at telomere →	-0.150	-1.173	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,853 associations by consensus.

Exploration

TPK1 survival (RNA) · tumor vs normal (RNA) · all TPK1 data types