TPI1

Across TCGA patient cohorts, TPI1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,742 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TPI1-associated proteins across cancer lineages are NOP2, TPI1_S80, and KDM3A. Each is linked with TPI1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TPI1-to-partner and partner-to-TPI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPI1 versus NOP2 in LUAD, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPI1→partner) and Y-score (partner→TPI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NOP2 →	+0.474	+0.629	<.001	<.001	3	8
PDAC	TPI1_S80 →	+0.683	+0.511	<.001	<.001	3	8
LSCC	KDM3A →	+0.391	+0.475	<.001	<.001	3	7
OV	TPI1_S21 →	+0.717	+0.525	<.001	.003	3	7
LUAD	P4HA1 →	+0.670	+0.580	<.001	<.001	3	7
OV	DARS1 →	+0.267	+0.562	.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,742 associations by consensus.

TPI1 vs NOP2 — LUAD

Explore this scatter interactively →