TPI1

Across TCGA patient cohorts, TPI1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,699 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPI1-associated genes across cancer lineages are MRPL51, GAPDH, and ENO2. Each is linked with TPI1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TPI1-to-partner and partner-to-TPI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPI1 versus MRPL51 in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPI1→partner) and Y-score (partner→TPI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MRPL51 →	+0.565	+0.337	<.001	<.001	3	6
UCEC	GAPDH →	+1.689	+0.286	<.001	<.001	3	6
LSCC	ENO2 →	+1.161	+0.270	<.001	<.001	3	6
OV	C1RL →	+0.805	+0.447	<.001	<.001	3	6
OV	PEX5 →	+0.867	+0.679	<.001	<.001	3	6
UCEC	PPFIA4 →	+1.086	+0.301	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,699 associations by consensus.

TPI1 vs MRPL51 — LSCC

Explore this scatter interactively →