TPI1

Across TCGA cell cohorts, TPI1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TPI1-associated genes across cancer lineages are MS4A4A and ZNF831. Each is linked with TPI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPI1-to-partner and partner-to-TPI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A4A grouped by TPI1-low versus TPI1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPI1→partner) and Y-score (partner→TPI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MS4A4A →	+0.174	+3.000	<.001	.006	3	1
LARGE_INTESTINE	ZNF831 →	+0.011	+3.103	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MS4A4A by TPI1 expression — LARGE_INTESTINE

Explore this box plot interactively →