TPGS1

Across TCGA patient cohorts, TPGS1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,172 significant associations in total. OV shows the largest number of these associations.

The most reproducible TPGS1-associated genes across cancer lineages are ARL3, CBY1, and SFXN3. Each is linked with TPGS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TPGS1-to-partner and partner-to-TPGS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPGS1 versus ARL3 in UCEC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPGS1→partner) and Y-score (partner→TPGS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARL3 →	+0.875	+0.812	<.001	.002	3	3
UCEC	CBY1 →	+0.703	+0.751	.001	.004	3	2
HNSC	SFXN3 →	+1.322	+2.225	<.001	<.001	3	2
OV	SPTBN1 →	+1.400	+0.628	.001	.009	3	2
HNSC	CEMIP2 →	+1.837	+2.085	.003	.001	3	2
UCEC	PAPSS1 →	+1.260	+0.644	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,172 associations by consensus.

TPGS1 vs ARL3 — UCEC

Explore this scatter interactively →