TPD52L3

Across TCGA patient cohorts, TPD52L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,166 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TPD52L3-associated GO terms across cancer lineages are Mitochondrial gene expression, Cytoplasmic translation, and Positive regulation of cell growth. Each is linked with TPD52L3 in more than 10 cancer types. Because this analysis shows association rather than direction, both TPD52L3-to-partner and partner-to-TPD52L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by TPD52L3-low versus TPD52L3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPD52L3→partner) and Y-score (partner→TPD52L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.064	+0.073	<.001	<.001	3	10
ESCA	Cytoplasmic translation →	+0.126	+0.070	<.001	.006	2	10
STAD	Positive regulation of cell growth →	+0.043	+0.064	<.001	<.001	3	9
STAD	Stress-activated protein kinase signaling cascade →	+0.051	+0.063	<.001	<.001	3	9
ESCA	Developmental cell growth →	+0.056	+0.064	<.001	.009	1	11
STAD	Protein insertion into membrane →	+0.057	+0.073	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,166 associations by consensus.

Mitochondrial gene expression by TPD52L3 expression — STAD

Explore this box plot interactively →