TPD52L3

Across TCGA cell cohorts, TPD52L3 RNA expression is significantly associated with the mutation status of many other genes, with 138 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TPD52L3-associated genes across cancer lineages are GABRA5, SLC7A9, and AARS1. Each is linked with TPD52L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPD52L3-to-partner and partner-to-TPD52L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GABRA5 grouped by TPD52L3-low versus TPD52L3-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPD52L3→partner) and Y-score (partner→TPD52L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GABRA5 →	+4.643	+0.013	.008	<.001	3	2
LUNG_NSCLC_LUSC	SLC7A9 →	+4.643	+0.013	.008	<.001	3	2
LUNG_NSCLC_LUSC	AARS1 →	+4.643	+0.013	.008	<.001	3	2
LUNG_NSCLC_LUAD	CLCA4 →	+4.266	+0.263	.004	<.001	3	2
LUNG_NSCLC_LUAD	ZBTB49 →	+5.266	+0.395	.001	<.001	3	2
LUNG_NSCLC_LUAD	TAF2 →	+3.944	+0.225	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 138 associations by consensus.

GABRA5 by TPD52L3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →