TPD52L3

Across TCGA cell cohorts, TPD52L3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TPD52L3-associated genes across cancer lineages are OXT, MYF6, and IFNA8. Each is linked with TPD52L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPD52L3-to-partner and partner-to-TPD52L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OXT grouped by TPD52L3-low versus TPD52L3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPD52L3→partner) and Y-score (partner→TPD52L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OXT →	+0.070	+4.977	<.001	.007	3	1
SKIN	MYF6 →	+0.018	+4.977	.001	.007	3	1
SKIN	IFNA8 →	+0.021	+4.977	.001	.007	3	1
SKIN	C5orf52 →	+0.062	+5.415	<.001	.004	3	1
SKIN	KRTAP10-1 →	+0.019	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OXT by TPD52L3 expression — SKIN

Explore this box plot interactively →