TPD52L1

Across TCGA patient cohorts, TPD52L1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,657 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TPD52L1-associated genes across cancer lineages are HDDC2, LDHD, and SAMD12. Each is linked with TPD52L1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TPD52L1-to-partner and partner-to-TPD52L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPD52L1 versus HDDC2 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPD52L1→partner) and Y-score (partner→TPD52L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HDDC2 →	+0.563	+0.720	<.001	<.001	3	5
UCEC	LDHD →	+0.985	+0.507	.001	.003	3	5
LSCC	SAMD12 →	+1.089	+0.654	<.001	<.001	3	5
HNSC	SAMD12-AS1 →	+1.107	+0.428	.001	<.001	3	5
HNSC	STK4 →	-0.383	-0.390	<.001	<.001	3	4
HNSC	SAMHD1 →	-0.724	-0.509	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,657 associations by consensus.

TPD52L1 vs HDDC2 — LUAD

Explore this scatter interactively →