TPD52L1

Across TCGA patient cohorts, TPD52L1 mutation is significantly associated with the RNA expression of many other genes, with 754 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPD52L1-associated genes across cancer lineages are ANKRD49P3, BTBD6, and DRG1. Each is linked with TPD52L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPD52L1-to-partner and partner-to-TPD52L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD49P3 grouped by TPD52L1-low versus TPD52L1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPD52L1→partner) and Y-score (partner→TPD52L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	ANKRD49P3 →	+0.123	+5.039	.005	.008	3	2
UCEC	BTBD6 →	+0.421	+3.337	.009	.005	3	2
UCEC	DRG1 →	+0.556	+3.649	<.001	.001	3	2
UCEC	GPATCH3 →	+0.520	+3.638	.001	.001	3	2
UCEC	MTFP1 →	+0.905	+3.470	<.001	.002	3	2
UCEC	MIR924HG →	+0.611	+3.617	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 754 associations by consensus.

ANKRD49P3 by TPD52L1 expression — READ

Explore this box plot interactively →