TPD52

Across TCGA cell cohorts, TPD52 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,528 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TPD52-associated GO terms across cancer lineages are Extracellular matrix organization, Extracellular structure organization, and External encapsulating structure organization. Each is linked with TPD52 in more than 11 cancer types. Because this analysis shows association rather than direction, both TPD52-to-partner and partner-to-TPD52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Extracellular matrix organization grouped by TPD52-low versus TPD52-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPD52→partner) and Y-score (partner→TPD52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Extracellular matrix organization →	-0.115	-1.732	<.001	.001	3	12
CNS	Extracellular structure organization →	-0.115	-1.732	<.001	.001	3	12
CNS	External encapsulating structure organization →	-0.115	-1.732	<.001	.001	3	12
BREAST	Receptor recycling →	+0.047	+1.011	.005	.002	3	9
BONE	Signal transduction in response to DNA damage →	+0.095	+2.830	.002	.001	3	8
BLOOD_Leukemia	Morphogenesis of an epithelium →	-0.034	-2.056	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,528 associations by consensus.

Extracellular matrix organization by TPD52 expression — CNS

Explore this box plot interactively →