Across TCGA patient cohorts, TPCN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,525 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TPCN1-associated proteins across cancer lineages are TK2, ABCE1, and MYBBP1A_S1241. Each is linked with TPCN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TPCN1-to-partner and partner-to-TPCN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPCN1→partner) and Y-score (partner→TPCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TK2 →	+0.328	+0.737	<.001	<.001	3	4
BRCA	ABCE1 →	-0.363	-0.937	<.001	<.001	3	4
BRCA	MYBBP1A_S1241 →	-0.730	-0.751	.009	.001	3	3
BRCA	MICALL1_S621 →	-0.536	-0.617	<.001	<.001	3	3
OV	PTPA →	+0.409	+0.814	.004	.004	3	3
LUAD	IRF2BP1_S66 →	-0.618	-0.495	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,525 associations by consensus.

Exploration

TPCN1 survival (RNA) · tumor vs normal (RNA) · all TPCN1 data types