Across TCGA cell cohorts, TPCN1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,682 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TPCN1-associated genes across cancer lineages are IQCD, HECTD4, and UBE3B. Each is linked with TPCN1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TPCN1-to-partner and partner-to-TPCN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPCN1→partner) and Y-score (partner→TPCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	IQCD →	+1.935	+2.145	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	HECTD4 →	+1.346	+1.610	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	UBE3B →	+0.856	+1.507	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	TSC2 →	+1.185	+1.543	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	RUSF1 →	+1.232	+1.594	<.001	<.001	3	10
OESOPHAGUS	SLC8B1 →	+1.229	+1.337	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,682 associations by consensus.

Exploration

TPCN1 survival (RNA) · tumor vs normal (RNA) · all TPCN1 data types