TPBGL

Across TCGA patient cohorts, TPBGL RNA expression is significantly associated with the go_rna of many other GO terms, with 7,154 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TPBGL-associated GO terms across cancer lineages are Regulation of mononuclear cell migration, Negative regulation of alpha-beta T cell activation, and Negative regulation of hemopoiesis. Each is linked with TPBGL in more than 18 cancer types. Because this analysis shows association rather than direction, both TPBGL-to-partner and partner-to-TPBGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mononuclear cell migration grouped by TPBGL-low versus TPBGL-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPBGL→partner) and Y-score (partner→TPBGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of mononuclear cell migration →	+0.066	+0.597	<.001	.001	3	19
DLBC	Negative regulation of alpha-beta T cell activation →	+0.082	+0.616	.004	<.001	3	19
ESCA	Negative regulation of hemopoiesis →	+0.052	+0.717	<.001	<.001	3	19
PAAD	Platelet-derived growth factor receptor-beta signaling pathway →	+0.087	+0.494	<.001	<.001	3	19
ESCA	Integrin-mediated signaling pathway →	+0.068	+0.713	<.001	<.001	3	18
ESCA	Regulation of cell shape →	+0.066	+0.751	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,154 associations by consensus.

Regulation of mononuclear cell migration by TPBGL expression — ESCA

Explore this box plot interactively →