TPBGL

Across TCGA patient cohorts, TPBGL protein abundance is significantly associated with the protein abundance of many other proteins, with 412 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TPBGL-associated proteins across cancer lineages are TRPV2_S741, VPS4A, and WNK1_S1035. Each is linked with TPBGL in more than 1 cancer types. Because this analysis shows association rather than direction, both TPBGL-to-partner and partner-to-TPBGL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPBGL versus TRPV2_S741 in GBM, with a Pearson correlation of 0.79.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPBGL→partner) and Y-score (partner→TPBGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRPV2_S741 →	+1.605	+0.678	<.001	<.001	3	1
GBM	VPS4A →	-0.251	-0.751	.005	.003	3	1
GBM	WNK1_S1035 →	-0.785	-0.818	.003	<.001	3	1
GBM	REXO1_S610 →	+0.264	+0.678	.002	<.001	3	1
GBM	RTKN_S520 →	-0.513	-0.646	.001	<.001	3	1
GBM	SAP130_S442 →	+0.568	+0.702	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 412 associations by consensus.

TPBGL vs TRPV2_S741 — GBM

Explore this scatter interactively →