TPBGL

Across TCGA cell cohorts, TPBGL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,902 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TPBGL-associated GO terms across cancer lineages are Regulation of hair follicle development, Regulation of myoblast fusion, and Transcription preinitiation complex assembly. Each is linked with TPBGL in more than 7 cancer types. Because this analysis shows association rather than direction, both TPBGL-to-partner and partner-to-TPBGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hair follicle development grouped by TPBGL-low versus TPBGL-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPBGL→partner) and Y-score (partner→TPBGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of hair follicle development →	-0.191	-0.640	.001	.004	3	7
BLOOD_Leukemia	Regulation of myoblast fusion →	+0.071	+0.030	<.001	.006	2	8
BONE	Transcription preinitiation complex assembly →	+0.072	+0.288	<.001	.001	3	6
BLOOD_Lymphoma	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.064	+0.003	<.001	.003	3	6
BONE	DNA-templated transcription initiation →	+0.084	+0.183	.002	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.064	+0.103	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,902 associations by consensus.

Regulation of hair follicle development by TPBGL expression — SKIN

Explore this box plot interactively →