Across TCGA pan-cancer cohorts, TP73-AS1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TP73-AS1 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher TP73-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TP73-AS1 expression acts as an unfavorable survival marker.

READ and LUSC are the cancer types where TP73-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	III,IV	0.289	0.932	<.001	15	view →
LUSC	OS	Median	All	0.152	0.762	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TP73-AS1 tumor-vs-normal RNA expression · all TP73-AS1 data types