Across TCGA pan-cancer cohorts, TP53TG3HP RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TP53TG3HP’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TP53TG3HP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TP53TG3HP is over-expressed in tumor.
HNSC and LUSC are the cancer types where TP53TG3HP tumor–normal differential expression is most reproducible.