TP53TG3B

Across TCGA cell cohorts, TP53TG3B RNA expression is significantly associated with the go_rna of many other GO terms, with 992 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible TP53TG3B-associated GO terms across cancer lineages are Regulation of isotype switching to IgE isotypes, Positive regulation of isotype switching to IgE isotypes, and RISC complex assembly. Each is linked with TP53TG3B in more than 4 cancer types. Because this analysis shows association rather than direction, both TP53TG3B-to-partner and partner-to-TP53TG3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of isotype switching to IgE isotypes grouped by TP53TG3B-low versus TP53TG3B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53TG3B→partner) and Y-score (partner→TP53TG3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of isotype switching to IgE isotypes →	-1.284	-0.734	<.001	.004	3	4
LUNG_NSCLC_LUSC	Positive regulation of isotype switching to IgE isotypes →	-1.284	-0.734	<.001	.004	3	4
LUNG_NSCLC_LUSC	RISC complex assembly →	+0.086	+0.763	.003	.001	3	4
LUNG_NSCLC_LUSC	Keratinocyte differentiation →	-0.111	-0.751	.007	.005	3	4
LUNG_NSCLC_LUSC	Retinal ganglion cell axon guidance →	-0.260	-0.840	<.001	.001	3	4
LUNG_NSCLC_LUSC	Neurofilament bundle assembly →	+1.799	+0.871	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 992 associations by consensus.

Regulation of isotype switching to IgE isotypes by TP53TG3B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →