TP53TG3

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, TP53TG3 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TP53TG3’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where TP53TG3 RNA is repressed in tumor relative to normal tissue. In most cancer types TP53TG3 is over-expressed in tumor, although a few such as UCEC and KIRC show the opposite, repressed pattern.

UCEC, LUSC, and KIRC are the cancer types where TP53TG3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TP53TG3 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
UCECAllAll−0.007.0182view →
LUSCAllAll+0.006.0012view →
KIRCAllAll−0.002.0271view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration