TP53INP2

Across TCGA patient cohorts, TP53INP2 mutation is significantly associated with the RNA expression of many other genes, with 737 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TP53INP2-associated genes across cancer lineages are TXN2P1, GOLGA8EP, and RNVU1-33. Each is linked with TP53INP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53INP2-to-partner and partner-to-TP53INP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXN2P1 grouped by TP53INP2-low versus TP53INP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53INP2→partner) and Y-score (partner→TP53INP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TXN2P1 →	+0.326	+2.617	.001	.006	3	2
CESC	GOLGA8EP →	+0.019	+3.874	<.001	.006	3	1
CESC	RNVU1-33 →	+0.187	+3.816	.002	.007	3	1
CESC	SNORD116-2 →	+0.696	+4.234	<.001	.003	3	1
CESC	MIR548A3 →	+0.445	+3.996	<.001	.005	3	1
CESC	CPLX3 →	+0.013	+4.757	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 737 associations by consensus.

TXN2P1 by TP53INP2 expression — UCEC

Explore this box plot interactively →