TP53INP1

Across TCGA patient cohorts, TP53INP1 mutation is significantly associated with the RNA expression of many other genes, with 1,043 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TP53INP1-associated genes across cancer lineages are RPL35AP15, DRD2, and GLB1L2. Each is linked with TP53INP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53INP1-to-partner and partner-to-TP53INP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL35AP15 grouped by TP53INP1-low versus TP53INP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53INP1→partner) and Y-score (partner→TP53INP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL35AP15 →	+0.249	+5.145	<.001	.007	3	2
UCEC	DRD2 →	-0.467	-2.481	.005	.002	3	1
UCEC	GLB1L2 →	-0.953	-3.791	<.001	<.001	3	1
UCEC	ADAM33 →	-0.852	-3.647	.006	.001	3	1
UCEC	C20orf144 →	+0.294	+2.831	<.001	.001	3	1
UCEC	MRPL49 →	+0.533	+2.923	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,043 associations by consensus.

RPL35AP15 by TP53INP1 expression — COAD

Explore this box plot interactively →