TP53I11

Across TCGA patient cohorts, TP53I11 protein abundance is significantly associated with the RNA expression of many other genes, with 8,847 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TP53I11-associated genes across cancer lineages are PIK3R3, PRXL2B, and CALM3. Each is linked with TP53I11 in more than 3 cancer types. Because this analysis shows association rather than direction, both TP53I11-to-partner and partner-to-TP53I11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TP53I11 versus PIK3R3 in CCRCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53I11→partner) and Y-score (partner→TP53I11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PIK3R3 →	+1.045	+0.626	<.001	<.001	3	4
UCEC	PRXL2B →	+0.744	+0.430	<.001	<.001	3	4
GBM	CALM3 →	+0.449	+0.474	<.001	.004	3	4
CCRCC	ADGRF5-AS1 →	+0.539	+0.334	<.001	<.001	3	4
UCEC	DLG3 →	+0.689	+0.337	.001	.008	3	4
BRCA	TMC5 →	+1.797	+0.487	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,847 associations by consensus.

TP53I11 vs PIK3R3 — CCRCC

Explore this scatter interactively →